Yes. However, you will need to book a Flex Plus fare. You can book a one-way Flex Plus reward fare in every class, as long as you fly from one flight zone to another. They’re not valid for travel within a single zone. You can add one stopover on your journey, but your journey must take place in one continuous direction. You can purchase a one-way Flex Plus reward for 50% of the miles needed for a round-trip Flex Plus reward between the same airports.